Frequently Asked Questions


What is Twelve Twenty Eight?

Twelve Twenty Eight Wellness is a premier regenerative and aesthetic medical practice specializing in personalized precision medicine, advanced skin rejuvenation, and cellular health optimization. Founded by Dr. Joni Collins, DMS, PA-C, CAC, the practice integrates regenerative science, peptide therapy, microvascular health, and aesthetic artistry to restore balance, vitality, and beauty from the inside out.

What makes Twelve Twenty Eight Wellness different from other med spas?

By definition Twelve Twenty Eight is a Regenerative Precision medical practice. Unlike traditional med spas, Twelve Twenty Eight Wellness blends functional medicine, regenerative aesthetics, and evidence-based precision protocols. Because every day is another day of aging , Twelve Twenty Eight believes in ongoing care to truly THRIVE and not just to live. Every treatment is customized based on your biology, vascular health, and cellular needs measured through tools like the GlycoCheck™ Microvascular Health Score. and more We are blessed to be an advocate for your life. journey.

What is The 1228 Protocol™?

The 1228 Protocol™ is an award-winning regenerative treatment sequence designed by Dr. Joni Collins. It combines PRF (Platelet-Rich Fibrin), microneedling, peptides, bioharmonic frequency therapy, and cellular oxygenation in a structured monthly cycle to optimize collagen regeneration, vascular repair, and overall skin health. It’s both a medical treatment plan and a business licensing model for clinicians nationwide..

What services do you offer?

Twelve Twenty Eight Wellness offers a full suite of aesthetic and regenerative precision services, including:

  • 360 degree Optimization (mentally, physically, spiritually)

  • PRF and regenerative skin rejuvenation

  • PDO thread lifts and collagen induction

  • Bioidentical hormone replacement therapy (BHRT)

  • Peptide therapy and performance optimization after epigenetic testing

  • Cryotherapy and bioharmonic vibration therapy (V.I.B.E. 3.1 Bed)

  • Epigenetic and genomic testing for precision care

  • The 1228 Biohack™ and 1228 Precision Membership™ programs

  • Allogenic and Autologous Cell Therapy

  • Evidence based Pain Management for orthopedic and Autoimmune conditions without the use of medications

Each service is tailored to your unique physiology and long-term goals.

What is the 1228 Biohack™?

The 1228 Biohack™ is a personalized cellular optimization experience that merges genomic insights, peptides, PRF, oxygenation, and photobiomodulation to support energy, cognition, skin health, and longevity. It’s part of our annual Regenerative Precision Membership, designed to reverse biological aging and enhance performance.

What is the GlycoCheck™ Microvascular Health Score?

GlycoCheck™ is a state-of-the-art diagnostic system that measures the health of your microvascular glycocalyx—the lining that protects every capillary in your body. Your score reveals early signs of inflammation, vascular dysfunction, or aging. At Twelve Twenty Eight Wellness, this data guides your regenerative treatment plan for measurable, science-based results.

What is the Bioharmonic VIBE™ therapy?

The Bioharmonic VIBE 3.1 Bed™ integrates sound frequencies, vibration, and pulsed electromagnetic fields (PEMF) to restore cellular resonance and promote parasympathetic healing. It enhances lymphatic drainage, improves microcirculation, and complements our peptide, PRF, and precision protocols for a truly holistic regenerative experience.

What peptides do you use at Twelve Twenty Eight Wellness?

Our peptide protocols are fully personalized and clinically monitored. Common options include peptides for tissue repair, and for growth hormone support, mitochondrial health, and hormonal balance. Every plan is guided by functional lab markers, genomic data, and the patient’s specific cellular needs.

Who is Dr. Joni Collins DMS, PA-C, CAC?

Dr. Joni Collins, DMS, PA-C, CAC is a nationally recognized expert in regenerative precision and aesthetic medicine. She is an educator and creator of The 1228 Protocol™. She carries a rare blend of medical mastery and artistic precision. Her career spans Neonatal Intensive Care (NICU), Reproductive Endocrinology, Hospital Medicine, Trauma, Interventional Cardiology, Facial Plastics and Head & Neck Surgery, Precision Cellular and Advanced Therapies, Psychology, and Internal Medicine—plus lifelong training in Sculpture and Dance, which refined her anatomical and aesthetic eye. Dr. Collins holds over 45 advanced certifications in medicine, regenerative aesthetics, hormone therapy, peptides, and longevity science, making her one of the most cross-trained professionals in her field.

Are treatments at Twelve Twenty Eight Wellness FDA-approved?

All injectable, device-based, and biologic treatments at Twelve Twenty Eight Wellness use FDA-cleared products or devices within appropriate medical scope. Some regenerative or peptide therapies may be off-label but are supported by scientific literature, patient consent, and physician-supervised protocols.

How soon will I see results from regenerative treatments?

Results vary by treatment type, but most patients notice visible improvement in skin tone, clarity, and energy within 2–4 weeks. PRF and peptide therapies continue to build results for several months as collagen and vascular networks remodel. Longevity benefits—such as improved microvascular health—are measurable through repeat GlycoCheck™ testing.

Do you offer virtual consultations or national programs?

Yes. Twelve Twenty Eight Wellness provides virtual regenerative consultations and telewellness programs across the United States. These include precision medicine assessments, peptide protocols, and genomic consultations—all coordinated through secure, HIPAA-compliant platforms.

Can providers become licensed in The 1228 Protocol™?

Yes. Qualified medical providers (PA, NP, MD, DO) can license The 1228 Protocol™ and receive full clinical training, business support, and vendor access through TrainWith1228.com. The licensing model includes treatment protocols, business ROI frameworks, and exclusive regenerative partnerships curated by Dr. Joni Collins. you offer training for medical professionals?

Yes. Through TrainWith1228.com, Dr. Collins provides national certification courses for PAs, NPs, MDs, and DOs in regenerative aesthetics, peptides, PRF, microvascular health, and practice optimization. The 1228 Training Series™ is available both in person and online via Kajabi.

Where is Twelve Twenty Eight Wellness located?

Twelve Twenty Eight Wellness operates in Roswell, Georgia, with a mobile extension in Florida. Virtual consultations and tele-wellness programs are also available nationwide through our Precision Medicine Membership platform.

How can I get started?

You can schedule a New Patient Consultation or request a Precision Membership Discovery Call directly on our website:

www.1228wellness.com.
During your first visit, we’ll assess your vascular health, hormonal balance, and aesthetic goals to build your custom regenerative roadmap.

For training ? Checkout:

www.trainwith1228.com